139 Improvement of immunological tests for linear IgA bullous dermatosis

Linear IgA Bullous Dermatosis

Figure 1. Clinical photograph of linear IgA bullous dermatosis showing tense bullae and erosions involving the lower abdomen, inner thighs, and extremities.

Linear IgA and IgG bullous dermatosis*

Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous disease. It results in linear deposition of autoantibodies (immunoglobulin A) against antigens in the basal membrane zone, leading to subepidermal cleavage. Additional depositions of immunoglobulin G and complement-3 might occur. It is still debated whether concomitant findings of immunoglobulins A and G should be...

IgA LINEAR BULLOUS DERMATOSIS IN CHILDHOOD

http://www.journal-imab-bg.org / J of IMAB. 2015, vol. 21, issue 4/ ABSTRACT: IgA linear bullous dermatosis, also known as chronic bullous dermatosis of childhood, is an autoimmune disease which may be idiopathic or drug-induced. The disease affects children and adults. We present a 4 years old girl with itchy polymorphic eruptions. The skin rash was presented by bullous-erosive rosette-like le...

[Vancomycin-induced linear IgA bullous dermatosis].

[Drug induced linear IgA bullous dermatosis].

Linear IgA disease is an autoimmune subepidermal bullous disease in which linear IgA deposits are found at the basement membrane zone. It is classically idiopathic but a drug-induced variant seems to be individualized in which cutaneous lesions resolve spontaneously after cessation of responsible treatment. Among the commonly implicated drugs, vancomycin is the most frequently reported. One sho...